THE CURRENT CASE OF QUINOLONES: SYNTHETIC APPROACHES AND …
Web Mar 28, 2016 Quinolones are broad-spectrum synthetic antibacterial drugs first obtained during the synthesis of chloroquine. Nalidixic acid, the prototype of quinolones, first … From ncbi.nlm.nih.gov Author Abdul Naeem, Syed Lal Badshah, Syed Lal Badshah, Mairman Muska, Nasir Ahmad, Khalid KhanDOI 10.3390/molecules21040268Publish Year 2016Publication Molecules. 2016 Apr; 21(4)
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QUINOLONE ANTIBIOTICS - PMC - NATIONAL CENTER FOR BIOTECHNOLOGY …
Web Oct 1, 2019 The development of quinolones in terms of pharmacokinetics and pharmacodynamics relates to improvements in metabolism, elimination, and … From ncbi.nlm.nih.gov DOI 10.1039/c9md00120dPublished 2019/10/10Publication Medchemcomm. 2019 Oct 1; 10(10)
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QUINOLONES - STATPEARLS - NCBI BOOKSHELF
Web May 22, 2023 Quinolones are bactericidal antibiotics that directly kill bacterial cells. They act on bacterial type II topoisomerases, DNA … From ncbi.nlm.nih.gov Published 2023/05/22Author Amanda Yan, Emily E. Bryant
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LIST OF QUINOLONES: USES, COMMON BRANDS, AND SAFETY INFORMATION
Web Mar 28, 2022 There are several different types of antibiotics that may be used for various infections, but quinolones (also known as fluoroquinolones) are a type of infectious … From singlecare.com
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QUINOLONES | TREATMENT SUMMARIES | BNF | NICE
Web Ofloxacin is licensed for urinary-tract infections, lower respiratory-tract infections, gonorrhoea, and non-gonococcal urethritis and cervicitis. Levofloxacin is active against … From bnf.nice.org.uk
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QUINOLONES: CLINICAL USE AND FORMULARY CONSIDERATIONS - PUBMED
Web Quinolones are broad-spectrum antibiotics active primarily against aerobic gram-negative organisms. All quinolones have activity against oral anaerobes, but only trovafloxacin … From pubmed.ncbi.nlm.nih.gov
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MECHANISM OF QUINOLONE ACTION AND RESISTANCE | BIOCHEMISTRY
Web Feb 27, 2014 Abstract. Quinolones are one of the most commonly prescribed classes of antibacterials in the world and are used to treat a variety of bacterial infections in … From pubs.acs.org
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(PDF) QUINOLONE ANTIBIOTICS - RESEARCHGATE
Web Jun 28, 2019 PDF | The quinolone antibiotics arose in the early 1960s, with the first examples possessing a narrow-spectrum activity with unfavorable pharmacokinetic... | … From researchgate.net
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SOME ANTIBIOTICS ARE RISKIER THAN OTHERS: WHAT YOU SHOULD …
Web Quinolones are broad spectrum antibiotics, which means they are effective against a wide range of diseases caused by bacteria. They were approved by the FDA to treat … From center4research.org
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QUINOLONES: FROM ANTIBIOTICS TO AUTOINDUCERS - OXFORD ACADEMIC
Web Mar 1, 2011 Natural and synthetic quinolones of medicinal interest, quinolone antibiotics. Several plant, animal and microbial species produce quinolone compounds … From academic.oup.com
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THE QUINOLONES: PAST, PRESENT, AND FUTURE - OXFORD ACADEMIC
Web Jul 15, 2005 Quinolones also have documented effectiveness for treating uncomplicated (and some complicated) urinary tract infections, bacterial prostatitis, skin and other soft … From academic.oup.com
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NEW CLASSIFICATION AND UPDATE ON THE QUINOLONE ANTIBIOTICS
Web May 1, 2000 A new four-generation classification of the quinolone drugs takes into account the expanded antimicrobial spectrum of the more recently introduced … From aafp.org
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QUINOLONES | TREATMENT & MANAGEMENT | POINT OF CARE - STATPEARLS
Web May 22, 2023 Many different quinolones have undergone development, and among them, the ones currently approved by the FDA for systemic use include moxifloxacin, … From statpearls.com
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QUINOLONE ANTIBIOTIC - WIKIPEDIA
Web Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. They are used in human … From en.wikipedia.org
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QUINOLONES: A COMPREHENSIVE REVIEW | AAFP
Web Feb 1, 2002 Marginal susceptibility and acquired resistance limit the usefulness of second-generation quinolones in the treatment of staphylococcal, streptococcal, and … From aafp.org
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QUINOLONES | DRUGBANK ONLINE
Web Quinolones. A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID. A fluoroquinolone antibiotic used to treat various bacterial … From go.drugbank.com
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MECHANISM OF QUINOLONE ACTION AND RESISTANCE - PMC
Web Mar 3, 2014 Over a period of a few decades, quinolones have transformed from a small and unimportant class of drugs used primarily to treat urinary tract infections to some of … From ncbi.nlm.nih.gov
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QUINOLONE ANTIBIOTICS - MEDCHEMCOMM (RSC …
Web Jun 28, 2019 The quinolone class of antibiotics inhibits the DNA synthesis of bacteria by disrupting the bacterial topoisomerase type II; inhibiting the catalytic activity of DNA gyrase and topoisomerase IV. 8 … From pubs.rsc.org
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QUINOLONE ANTIBIOTICS: RESISTANCE AND THERAPY - PMC
Web Feb 10, 2023 This review is focusing on the drug discovery history, compound structure, and bactericidal mechanism of quinolone antibiotics. Recent studies bring a more in … From ncbi.nlm.nih.gov
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QUINOLONES: MECHANISM, LETHALITY AND THEIR CONTRIBUTIONS TO …
Web Dec 1, 2020 Sparfloxacin and moxifloxacin () are the better-known compounds of the third and fourth generations, respectively, and are amongst the first quinolones to show … From ncbi.nlm.nih.gov
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OUR EVOLVING UNDERSTANDING OF THE MECHANISM OF QUINOLONES
Web Apr 8, 2018 By chronologically analyzing data gathered on the mode of action of this imperative antibiotic class, we highlight the necessity to look beyond primary drug-target … From ncbi.nlm.nih.gov
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QUINOLINES AND QUINOLONES AS ANTIBACTERIAL, ANTIFUNGAL, ANTI
Web Sep 13, 2019 The drugs based on quinoline/quinolone structure are well-known and in use for over half a century in the treatment of bacterial, parasitic, and viral infections. … From link.springer.com
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